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Drug interactions with Tadalafil 20mg
The breakdown and elimination of Tadalafil from the body may be decreased by erythromycin, ketoconazole (Nizoral), itraconazole (Sporanox), and ritonavir (Norvir). Therefore, these drugs may increase the levels of Tadalafil in the blood. If these drugs are being used at the same time as Tadalafil, the dose of Tadalafil should be reduced in order to avoid side effects from high levels of Tadalafil.
Tadalafil exaggerates the increases in heart rate and lowering of blood pressure caused by nitrates, for example, nitroglycerin, that is used primarily for treating heart pain (angina). In patients who take nitrates for angina, Tadalafil could cause heart pain or possibly even a heart attack by exaggerating the increase in heart rate and the lowering of blood pressure. Therefore, Tadalafil should not be used with nitrates.
Important information about Tadalafil 20mg
Do not use Tadalafil if you become dizzy or nauseated during sexual activity, or if you have pain, numbness, or tingling in your chest, arms, neck, or jaw, call your doctor right away. You could be having a serious side effect of Tadalafil.
Do not take Tadalafil more than once a day. Allow 24 hours to pass between doses. Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis.
Tadalafil can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people taking Tadalafil, most of whom also had heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoke or are over 50 years old. It is not clear whether Tadalafil is the actual cause of vision loss.
Stop using Tadalafil and get emergency medical help if you have sudden vision loss.
Before taking Tadalafil 20mg
Do not take Tadalafil if you have any of these other conditions: you may need a Tadalafil dose adjustment or special tests:
• heart disease or heart rhythm problems;
• a recent heart attack (within the past 90 days);
• a recent history (within the past 6 months) of stroke or congestive heart failure;
• angina (chest pain), high or low blood pressure;
• liver disease;
• kidney disease (or if you are on dialysis);
• a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia;
• a bleeding disorder such as hemophilia;
• a stomach ulcer;
• retinitis pigmentosa (an inherited condition of the eye);
• a physical deformity of the penis (Peyronie's disease); or
• if you have been told you should not have sexual intercourse for health reasons.
Tadalafil is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether Tadalafil passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Tadalafil side effects:
Stop using Tadalafil and call your doctor at once if you have any of these serious side effects:
changes in vision or sudden vision loss; ringing in your ears, or sudden hearing loss; chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling; irregular heartbeat; shortness of breath, swelling in your hands, ankles, or feet; seizure (convulsions); feeling light-headed, fainting; or
penis erection that is painful or lasts 4 hours or longer.
Less serious Tadalafil side effects may include:
redness or warmth in your face, neck, or chest; cold symptoms such as stuffy nose, sneezing, or sore throat; headache; memory problems; diarrhea, upset stomach; or muscle pain, back pain.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
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